Does elevated transaminase levels mean liver disease?
Disease description:
During the examination, the data showed that my transaminase levels were high. I would like to ask, does having high transaminase levels mean I have liver disease?
Doctor's answer (1)
Dr. Yang Ziqi
Elevated transaminase levels do not necessarily indicate liver disease, but they are a common indicator of abnormal liver function. There are mainly two types of transaminases: alanine aminotransferase (ALT) and aspartate aminotransferase (AST), which are primarily found in liver cells. When liver cells are damaged, these enzymes are released into the bloodstream, causing elevated transaminase levels. Common causes of elevated transaminases include:
1. Hepatitis (viral, alcoholic, or drug-induced): This is one of the most common causes.
2. Fatty liver disease, caused by excessive fat accumulation in the liver.
3. Excessive alcohol consumption or long-term alcohol use.
To determine the exact cause, doctors usually combine medical history, physical examination, and other laboratory tests (such as a full liver function panel, hepatitis B and C virus testing). If transaminase levels remain elevated, prompt medical attention is advised.
