
Causes of Elevated Aspartate Aminotransferase (AST)
I often drink alcohol for social and business purposes. Over time, I have started to feel that my liver might be having issues. My medical checkup results show that my aspartate aminotransferase (AST) level is elevated. I would like to ask the doctor, what are the causes of elevated aspartate aminotransferase levels?

Aspartate aminotransferase (AST, also known as glutamic-oxaloacetic transaminase) levels that are higher than normal usually indicate liver damage. Below are some common causes that may lead to elevated AST levels:
1. Hepatitis: Viral hepatitis (such as hepatitis A, B, or C) is a common cause and can occur acutely or chronically.
2. Non-alcoholic fatty liver disease (NAFLD) or alcoholic fatty liver disease may also cause elevated AST levels.
3. Medications or toxins: Certain drugs (such as excessive acetaminophen), chemicals, or poisons can damage the liver and cause increased AST levels.
4. Other diseases: Fatty liver, myocardial infarction or muscle injury, cirrhosis, liver cancer, bile duct obstruction, pancreatitis, thyroid disorders, and other conditions may also affect AST levels.
If AST levels are elevated, it is recommended to seek medical attention promptly.