Can people with high uric acid levels drink red wine?

Jul 15, 2024 Source: Cainiu Health
Disease description:

I have always had the habit of drinking some red wine in the evening. Recently, my health has not been very good, and my uric acid levels were found to be somewhat elevated during a recent checkup. I would like to ask, can people with high uric acid levels drink red wine?

Doctor's answer (1)
Dr. Yang Ziqi
People with high uric acid levels are not advised to drink red wine. The reasons are as follows: 1. **Impact on purine metabolism**: Although red wine is not high in purines, it contains guanosine monophosphate (GMP), which is metabolized into purines in the body. This may increase the overall purine load, thereby affecting uric acid metabolism and potentially further elevating uric acid levels. 2. **Effect of alcohol**: The alcohol content in red wine places stress on the metabolic functions of the liver and kidneys, inhibiting the excretion of uric acid and thereby increasing blood uric acid concentration. 3. **Risk of disease**: Long-term high uric acid levels can lead to deposition of urate crystals in joints, soft tissues, and other areas, potentially triggering gout and other related diseases. Alcohol consumption, especially of red wine, may exacerbate this risk.