Can Sacubitril/Valsartan Sodium Tablets be taken with low blood pressure?

Aug 13, 2024 Source: Cainiu Health
Disease description:

My blood pressure is somewhat low, and I have chronic heart failure. My doctor prescribed me sacubitril/valsartan sodium tablets. May I ask, are sacubitril/valsartan sodium tablets suitable for use with low blood pressure?

Doctor's answer (1)
Dr. Tian Hongbo

Patients with hypotension can use Sacubitril Valsartan Sodium Tablets. Sacubitril Valsartan Sodium Tablets are medications used to treat chronic heart failure. They consist of Sacubitril, a neprilysin inhibitor, and Valsartan, an angiotensin receptor antagonist. These components primarily work by improving cardiac function and reducing vascular resistance.

If the patient's hypotension is caused by heart failure and is not severe enough to cause symptoms or affect organ perfusion, Sacubitril Valsartan Sodium Tablets may be considered. However, when systolic blood pressure is less than 90 mmHg and diastolic blood pressure is less than 60 mmHg, administration is not recommended, as it may lead to drug-induced hypotension.

If excessively low blood pressure occurs after taking Sacubitril Valsartan Sodium Tablets, the dosage should be adjusted or the medication discontinued promptly. Specific adjustments should be based on the patient's clinical condition and according to the physician's recommendations.

During treatment with Sacubitril Valsartan Sodium Tablets, patients should maintain a low-salt, low-fat diet and avoid emotional fluctuations and sleep deprivation, as these factors may affect blood pressure. Patients with abnormal blood pressure should regularly monitor blood pressure changes and adjust their treatment plans accordingly.