Long-term side effects of taking glucosamine

Aug 21, 2024 Source: Cainiu Health
Disease description:

During this period, my feet have consistently felt sore and painful. After going to the hospital for examination, I was prescribed some glucosamine. I would like to ask whether this medication could cause any side effects?

Doctor's answer (1)
Dr. Shen Yonghua

Possible side effects of long-term glucosamine use:

1. Gastrointestinal discomfort: This is one of the most common side effects, including stomach pain, nausea, diarrhea, or constipation. These symptoms are usually mild and temporary, but may persist in some individuals.

2. Allergic reactions: A small number of patients may experience allergic reactions, such as rash, itching, facial swelling, or difficulty breathing. This is because glucosamine is commonly derived from the shells of crustaceans like shrimp and crab, so individuals allergic to seafood should use it with caution.

3. Blood sugar level fluctuations: Although rare, glucosamine may affect blood sugar control, especially in individuals with diabetes. Therefore, diabetic patients should consult their doctor before using glucosamine.

4. Drug interactions: Glucosamine may interact with certain medications, affecting their effectiveness or increasing the risk of side effects. For example, glucosamine might enhance the effects of blood thinners, increasing the risk of bleeding.

If asthma symptoms worsen during glucosamine use, discontinue the medication promptly and seek medical attention.