After receiving an intravenous infusion, many red, itchy spots appeared on the body. Why is this happening?

Jun 04, 2025 Source: Cainiu Health
Disease description:

After I finished my IV drip, I suddenly developed a lot of red spots on my body, and they are very itchy—becoming even redder when scratched. Could this be an allergic reaction? What should I do?

Doctor's answer (1)
Dr. Liu Wenmin

In clinical practice, some patients may develop red skin spots accompanied by itching after receiving intravenous infusion therapy.

Drug allergy is a common cause. Patients may have an allergic reaction to the administered medication, resulting in red spots and itching. In such cases, the infusion should be stopped immediately, and the physician should be informed to allow prompt administration of anti-allergic treatment.

If infusion equipment is not properly sterilized or the solution becomes contaminated, it may cause localized or systemic infection, presenting as red spots and itching. Prolonged infusion or irritation of the blood vessel walls by the drug may lead to local skin reactions. Rapid or excessive infusion may increase intravascular fluid pressure, causing blood cells to aggregate within the capillaries and form red spots. In such cases, the infusion rate and volume should be adjusted, and antihypertensive medications may be used if necessary.

Upon noticing any abnormal reactions, the infusion should be stopped immediately and healthcare personnel notified. The physician will evaluate the severity of symptoms to determine whether anti-allergic medications are needed, whether the infusion plan should be adjusted, or if further investigation is required.