What are the side effects of Domperidone?

Jul 19, 2024 Source: Cainiu Health

Dr. Yang Ziqi

Introduction

1. May cause diarrhea. After taking domperidone, some people may experience symptoms such as dry mouth, constipation, diarrhea, or abdominal pain. 2. May induce lactation. Some patients may develop galactorrhea in women or gynecomastia in men while taking domperidone. 3. Endocrine disorders. Since domperidone does not easily cross the blood-brain barrier, it is considered to have no inhibitory effect on central dopamine receptors.

Under normal circumstances, "Ma Ding Ning" refers to domperidone tablets, which may cause side effects such as diarrhea, dizziness, breast tenderness, itching, and tachycardia. If discomfort occurs, it is recommended to seek medical attention promptly. A detailed analysis is as follows:

1. Diarrhea

Domperidone tablets act on the gastrointestinal tract, enhancing gastrointestinal motility and tone and promoting gastric emptying. However, this process may sometimes lead to excessive contraction of gastrointestinal smooth muscles, thereby causing diarrhea.

2. Dizziness

Although domperidone has low permeability across the blood-brain barrier, a small number of patients may still experience effects on the central nervous system, leading to dizziness.

3. Breast Tenderness

Domperidone is a prolactin-releasing agent. Long-term or excessive use may increase serum prolactin levels, thereby causing breast tenderness.

4. Itching

Some patients may develop allergic reactions to certain components in domperidone tablets, resulting in itching of the skin or mucous membranes.

5. Tachycardia

Domperidone may affect cardiac electrophysiological activity or increase cardiac workload, potentially leading to adverse cardiovascular reactions.

To ensure safety, always consult a healthcare professional before using any medication and follow medical instructions carefully. During treatment, monitor your body's response closely. If any abnormal reactions occur, communicate with your doctor promptly to adjust the treatment plan.

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