Symptoms of HPV infection
According to current clinical medical research, many individuals are asymptomatic carriers of the human papillomavirus (HPV). When a person’s overall health is good, this virus typically causes no harm. However, once immune function declines—or if an individual becomes newly infected—prompt medical treatment is essential; otherwise, HPV infection may cause significant damage to health.
Symptoms of HPV Infection
1. Light-red papules
The classic early sign of HPV infection is the appearance of small, fine, light-red papules. Over time, these lesions gradually increase in both size and number. Their surfaces become elevated and typically feel fragile yet firm to the touch. They manifest as irregular, warty hyperplasias. Clinically, genital warts (caused by HPV) exhibit diverse morphologies—including fungiform, cockscomb-like, cauliflower-like, and papillomatous forms—demonstrating considerable variability in appearance.

2. Bleeding during intercourse
Genital warts caused by HPV display variable surface colors—ranging from red to gray or matching normal skin tone—and tend to occur in moist areas. Additionally, a minority of patients experience pruritus (itching) of the genital region, pain or bleeding during sexual intercourse. Persistent itching often leads patients to scratch the affected area repeatedly, resulting in trauma to the warts, erosion, and even bleeding—which may subsequently lead to secondary infection.
3. Genital herpes-like manifestations
In males, HPV infection commonly affects the prepuce (foreskin), frenulum, glans penis, coronal sulcus, and urethral meatus; less frequently, it involves the penile shaft. In females, common sites include the external genitalia, vagina, perianal region, and cervix; simultaneous involvement of two or more of these sites is relatively common. Among men who have sex with men (MSM), anal and rectal involvement is typical, whereas scrotal infection is rare. Beyond these typical locations, HPV can also affect other anatomical sites—including interdigital spaces, umbilical fossa, oral cavity, and axillae.
The above outlines key clinical manifestations associated with HPV infection. We hope this information is helpful to you.