Which traditional Chinese medicines cause renal failure?
Apr 02, 2022
Source: Cainiu Health
Dr. Zhao Xinju
Introduction
Clinically, traditional Chinese medicines (TCMs) that may cause renal failure are primarily those containing *Aristolochia manshuriensis* (Guān Mù Tōng) or aristolochic acids. Some patients, upon developing illnesses, prefer TCM treatment; however, it is essential to seek care at a reputable traditional Chinese medicine hospital and consult qualified TCM practitioners who can prescribe appropriate herbal remedies based on the individual’s specific condition—self-administration of TCMs should be strictly avoided.
Renal failure generally refers to kidney failure—a pathological condition in which partial or complete loss of kidney function occurs as chronic kidney disease progresses to an advanced stage. Below, we address the question: Which traditional Chinese medicines (TCMs) can cause renal failure?
Which Traditional Chinese Medicines Can Cause Renal Failure?
Clinically, TCMs containing *Aristolochia manshuriensis* (Guanmutong) or aristolochic acid are the primary culprits associated with renal failure. Some patients prefer using TCMs to treat their illnesses; however, it is essential to seek care at a reputable TCM hospital and consult a qualified TCM practitioner who can prescribe appropriate herbal formulations based on individual diagnosis. Self-administration of TCMs without professional guidance should be strictly avoided. Not all TCMs are safe—certain herbs, such as those containing aristolochic acid or Guanmutong, may cause organ damage, particularly to the kidneys.
These two substances primarily induce chronic interstitial nephritis, damaging the renal interstitium. Affected patients often experience polyuria (increased urine output) and decreased urine specific gravity. Once renal interstitial cells are injured, patients may develop anemia. As the disease progresses, serum creatinine levels rise, indicating diminished renal excretory capacity—signaling the onset of renal failure.
The above outlines which TCMs may lead to renal failure. We hope this information is helpful to you.
