Symptoms and Manifestations of Pathological Jaundice
Pathological jaundice refers to elevated bilirubin levels caused by underlying pathological conditions. Some newborns may develop physiological jaundice shortly after birth. So, what are the symptoms and manifestations of pathological jaundice?
Jaundice in newborns commonly results from conditions such as hemolytic disease of the newborn, neonatal infection, biliary tract malformations, and neonatal hepatitis. Specific clinical manifestations include:
① Early onset
In cases of pathological jaundice, symptoms appear early—typically within 24 hours after birth.

② Rapid progression
After developing pathological jaundice, parents may notice that the infant’s skin and other tissues rapidly take on a yellowish discoloration.
③ Prolonged duration
In full-term infants with pathological jaundice, jaundice typically persists beyond two weeks. In preterm infants, it may last longer than three weeks.
④ Frequent recurrence
A challenging feature of pathological jaundice is its tendency to recur. Even after symptoms subside, the condition may suddenly reappear—and often with greater severity than before.