Is it normal to have a high fever after receiving the 23-valent pneumococcal vaccine?
Sep 21, 2022
Source: Cainiu Health
Dr. Guo Xiheng
Introduction
High fever generally refers to hyperpyrexia. Developing a high fever after receiving the 23-valent pneumococcal vaccine may be a normal vaccine reaction. However, if the high fever is caused by a concurrent infection during vaccination, this is considered abnormal and requires timely appropriate treatment. If body temperature is below 38.5°C, physical cooling methods can be used.
High fever generally refers to hyperthermia. Developing a high fever after receiving the 23-valent pneumococcal vaccine may be a normal vaccine reaction. However, if the high fever is caused by cross-infection during vaccination, this is considered abnormal and requires timely appropriate treatment.
1. Normal situation
The 23-valent pneumococcal vaccine contains antigens extracted from pathogens—specifically, the bacteria that cause pneumonia. After vaccination, these antigens stimulate an immune response in the body. In a small number of individuals with more sensitive constitutions, this immune stimulation may trigger a strong reaction. For example, T lymphocytes and B lymphocytes may respond vigorously, producing immune responses and cytokines, which can lead to high fever. Fever caused by this mechanism is usually accompanied by normal mental status and appetite, and typically resolves after rest.
2. Abnormal situation
Vaccination sites often involve gatherings of people, increasing the risk of cross-infection. The high fever following vaccination might not be related to the vaccine itself but instead due to an upper respiratory tract infection acquired during the visit. In such cases, symptoms like lethargy and significantly decreased appetite often accompany the fever, and prompt medical evaluation at a hospital is recommended.
If body temperature remains below 38.5°C, physical cooling methods such as tepid sponge baths or ice packs may help reduce fever. If body temperature reaches or exceeds 38.5°C, antipyretic medications may be used under medical guidance. Additionally, it's important to get adequate rest, drink plenty of fluids, urinate frequently, stay warm, avoid chilling, maintain a light diet, and monitor body temperature regularly.
