Is it fine once the jaundice disappears in ABO hemolytic disease?

Mar 28, 2023 Source: Cainiu Health

Dr. Zhang Heyang

Introduction

ABO hemolytic disease is generally not resolved simply because jaundice has disappeared. Jaundice is one of the common symptoms of ABO hemolytic disease, which occurs due to blood type incompatibility between mother and fetus at birth or from a blood transfusion, leading the body to produce antibodies that attack foreign red blood cells, causing a hemolytic reaction. Therefore, the disappearance of jaundice does not mean that ABO hemolytic disease has been completely cured.

ABO hemolytic disease is generally not resolved simply because jaundice has disappeared. The detailed explanation is as follows:

ABO hemolytic disease occurs due to blood type incompatibility between the mother and fetus during delivery or from a blood transfusion, leading to the production of antibodies in the body that attack foreign red blood cells, causing a hemolytic reaction. Jaundice is one of the common symptoms of ABO hemolytic disease, resulting from deposition of free bilirubin released after hemolysis in the skin and mucous membranes. Therefore, the disappearance of jaundice does not mean that ABO hemolytic disease has been completely cured. Treatment options for ABO hemolytic disease include blood transfusions, immunosuppressive agents, and infusion of fresh frozen plasma. During treatment, it is essential to closely monitor the patient's clinical condition and blood parameters such as hemoglobin, platelet count, and bilirubin levels. If treatment is delayed or inadequate, ABO hemolytic disease may lead to severe complications, including renal failure, heart failure, and brain damage.

Therefore, if symptoms of ABO hemolytic disease occur, prompt medical attention and treatment are necessary. It is also important to maintain healthy lifestyle habits and avoid consuming spicy or irritating foods.

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