Swollen, itchy, red palms with small blisters

Swelling, itching, redness, and small blisters on the palms may be caused by conditions such as contact dermatitis, eczema, or dyshidrotic eczema. Treatment should be based on the specific underlying cause. Details are as follows:

1. Contact Dermatitis

This is usually caused by exposure to irritants or allergens, resulting in localized skin inflammation accompanied by varying degrees of itching and blistering. Under medical guidance, topical treatments such as compound acetic acid dexamethasone cream or halometasone cream can be applied.

2. Eczema

Eczema includes both acute and chronic forms and is a type of allergic skin disorder. Acute eczema develops rapidly, while chronic eczema has a longer disease course and may lead to symptoms such as red patches, small blisters, and oozing. Under medical supervision, topical medications such as desonide cream or tacrolimus ointment can be used for treatment.

3. Dyshidrotic Eczema (Pompholyx)

This condition may result from excessive internal damp-heat, recent high levels of mental stress, or autonomic nervous system dysfunction. It often presents with clear, fluid-filled blisters on the skin, accompanied by swelling or pain. Under medical guidance, oral medications such as prednisone acetate tablets or triterpenoid saponin tablets, or topical applications of mometasone furoate cream, may be used for treatment.

In addition to the above causes, similar symptoms may also be due to hand-foot-and-mouth disease, palmoplantar pustulosis, or tinea manuum (fungal infection of the hands). Avoid scratching with the hands and maintain cleanliness of the affected area.