What causes whole-body itching?

Generally, generalized itching may be caused by dry environment, clothing irritation, urticaria, eczema, cholecystitis, or other reasons. If any discomfort occurs, it is recommended to seek medical attention promptly and receive symptomatic treatment under the guidance of a qualified physician. Specific analysis is as follows:

1. Dry Environment

In winter or low-humidity environments, reduced moisture in the air can cause the skin to lose water easily, leading to dryness. This weakens the skin’s barrier function and increases susceptibility to external irritants, potentially resulting in whole-body itching. It is advisable to regularly apply moisturizing creams or lotions over the entire body, especially after bathing. Maintaining an appropriate indoor humidity level with the use of a humidifier is also recommended.

2. Clothing Irritation

Wearing rough-textured or non-breathable clothing that rubs against the skin may lead to generalized itching. Symptoms typically improve after switching to more comfortable clothing, and medication is usually not required.

3. Urticaria (Hives)

Urticaria is commonly triggered by food, medications, infections, or other allergens. When the body comes into contact with allergens such as certain foods, drugs, or pollen, the immune system releases mediators like histamine, which may cause blood vessel dilation and increased permeability, leading to widespread skin itching. Other symptoms may include difficulty breathing and throat swelling. Under medical supervision, patients may take antihistamines such as loratadine tablets, cetirizine hydrochloride drops, or chlorpheniramine maleate tablets for treatment.

4. Eczema

Eczema may result from a combination of factors including genetic predisposition, immune dysfunction, hormonal imbalances, and microbial infections. The release of various inflammatory mediators—such as histamine and leukotrienes—acts on nerve endings in the skin, increasing their sensitivity and causing itching all over the body. This is often accompanied by symptoms such as redness and papules. Patients may use medications such as mometasone furoate cream, halometasone cream, or cetirizine hydrochloride tablets as directed by a physician.

5. Cholecystitis

Cholecystitis is often caused by bacterial infection, obstruction of the bile duct, or impaired blood supply to the gallbladder. Inflammation can disrupt bile metabolism, causing bile salts to accumulate and irritate the skin, leading to generalized itching. Other symptoms may include jaundice and fatigue. Under a doctor's guidance, patients may use medications such as anti-inflammatory and bile-promoting tablets, Danshu capsules, or Jindan tablets for treatment.

To help relieve and prevent generalized itching, it is important to maintain clean and well-moisturized skin, wear comfortable clothing, avoid known allergens, maintain emotional well-being, and follow a balanced diet.