Can pregnant women use fosfomycin?
Generally, fosfomycin refers to fosfomycin sodium. The use of fosfomycin sodium is not recommended for pregnant women. The specific analysis is as follows:
Fosfomycin sodium is a broad-spectrum antibiotic effective in treating certain bacterial infections, but its safety for the fetus has not been sufficiently confirmed by clinical studies. Due to the unique physiological state during pregnancy, drug metabolism and distribution in the body may differ from those in non-pregnant conditions, potentially increasing the risk of adverse effects on the fetus. Fosfomycin sodium may cross the placental barrier and enter the fetal circulation, possibly causing adverse effects on fetal growth and development, including organ malformations and nervous system damage, among other serious consequences. Therefore, physicians generally adopt a conservative approach, avoiding the use of drugs whose safety has not been adequately established.
Pregnant women should maintain good health and prevent infections. If an infection occurs, they should consult a physician to determine the safest treatment option and use medications such as fosfomycin sodium with caution.