What should I do if my alanine aminotransferase (ALT) level is high?

　　Under normal circumstances, PGAT (pyruvate glutamic transaminase) refers to alanine aminotransferase (ALT). Elevated ALT levels may be caused by excessive fatigue, strenuous exercise, fatty liver disease, acute cholecystitis, viral hepatitis, and other reasons. Treatment options include general therapy and medication, under a doctor's guidance. Detailed analysis is as follows:

　　1. Excessive Fatigue

　　Excessive fatigue may cause vigorous liver cell metabolism, accelerating cell aging and rupture, thereby releasing more ALT into the bloodstream. It is important to maintain sufficient rest, avoid prolonged high-intensity work or exercise, and arrange sleep schedules reasonably.

　　2. Strenuous Exercise

　　During strenuous exercise, active metabolism in liver and muscle cells may cause partial cell rupture, releasing ALT. Exercise should be conducted gradually, avoiding sudden high-intensity activity, and proper warm-up and relaxation should be performed before and after workouts.

　　3. Fatty Liver Disease

　　Fatty liver disease may result from long-term high-fat diets, lack of exercise, and other factors leading to excessive fat accumulation within liver cells. Patients may experience abnormal liver cell metabolism, causing elevated ALT levels. Symptoms may also include discomfort in the liver area and abdominal distension. Under a doctor's guidance, medications such as polyene phosphatidylcholine capsules, silymarin capsules, and compound glycyrrhizin tablets may be used for treatment.

　　4. Acute Cholecystitis

　　Acute cholecystitis involves inflammation within the gallbladder, causing bile stasis and bile duct obstruction, which affects liver function. When liver cells are damaged by inflammation, ALT is released into the bloodstream, causing elevated levels. Symptoms may also include nausea and vomiting. Patients may follow medical advice to use medications such as anti-inflammatory and cholagogic tablets, Dan Ning tablets, tauroursodeoxycholic acid capsules, and others for treatment.

　　5. Viral Hepatitis

　　Viral hepatitis occurs when a viral infection damages liver cells, causing the release of elevated ALT levels into the bloodstream, resulting in the aforementioned condition. Patients may also experience symptoms such as jaundice and fatigue. Under a doctor's recommendation, patients may use medications such as entecavir dispersible tablets, tenofovir disoproxil fumarate tablets, and diammonium glycyrrhizinate injections for treatment.

　　In daily life, maintaining a healthy lifestyle is important, including reasonable scheduling of rest periods, avoiding excessive fatigue and strenuous exercise; limiting alcohol consumption, maintaining a balanced diet, and avoiding high-fat and high-calorie foods.