How many doses of the rabies vaccine are required for the initial vaccination?

Jan 24, 2025 Source: Cainiu Health
Dr. Wang Lei
Introduction
The number of initial rabies vaccine doses depends on the injection method. The five-dose regimen requires five injections, starting on the day of the bite (day 0), followed by injections on day 3, day 7, day 14, and day 28. The four-dose regimen requires four injections: two doses on day 0, and one dose each on day 7 and day 21.

Generally speaking, rabies vaccine refers to the vaccine for rabies. The number of initial rabies vaccinations required mainly depends on the chosen vaccination schedule. If the five-dose regimen is chosen, five shots are needed. If the four-dose regimen is chosen, four shots are required. For those with questions, it is recommended to seek medical advice promptly. Detailed explanation is as follows:

The five-dose regimen requires the first dose to be administered on the day of the bite or scratch, followed by additional doses on day 3, day 7, day 14, and day 28, for a total of five doses. The purpose of this schedule is to provide progressively enhanced immunity, allowing the body to develop longer-lasting protection.

The four-dose regimen involves receiving two doses on the day of the bite or scratch, with one dose administered in each arm. Then, one additional dose is given on day 7 and another on day 21. Including the initial doses, this regimen totals four shots. This vaccination approach is simpler and faster, enabling rapid activation of protective antibodies to further prevent rabies virus infection.

It should be noted that regardless of which vaccination method is chosen, the vaccine must be administered according to the scheduled timeline to avoid delays that may affect the immune response. Additionally, the vaccination should be completed under the guidance of a healthcare professional; self-administration should be avoided.

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