What are the side effects of Levofloxacin?
Feb 11, 2025
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Under normal circumstances, levofloxacin is available in tablet and capsule formulations. Its side effects include joint pain, photosensitivity reaction, glucose metabolism disorders, liver and kidney function damage, and psychiatric abnormalities. During the course of taking levofloxacin, excessive exposure to sunlight should be avoided. When going outdoors, protective measures against sunlight should be taken, such as wearing sun-protective clothing, a wide-brimmed hat, and applying sunscreen, in order to prevent the occurrence of photosensitivity reactions.
Generally, levofloxacin is available in various dosage forms such as tablets and capsules. Levofloxacin may cause side effects including joint pain, photosensitivity reactions, glucose metabolism disorders, liver and kidney function damage, and psychiatric abnormalities. A detailed analysis is as follows:
1. Joint Pain
Levofloxacin may cause damage to articular cartilage, particularly evident in weight-bearing joints such as the knee and hip joints, leading to symptoms including joint pain, swelling, increased pain during movement, and impaired walking and joint mobility.
2. Photosensitivity Reaction
After taking levofloxacin, skin sensitivity to ultraviolet light increases. When exposed to sunlight or UV lamps, the skin may easily develop symptoms such as redness, itching, rashes, and in severe cases, blisters or peeling.
3. Glucose Metabolism Disorders
This medication may interfere with insulin secretion or action, leading to abnormal blood glucose levels. Some patients may experience symptoms of hypoglycemia, such as palpitations, sweating, fatigue, and dizziness; while others may develop hyperglycemia, presenting with symptoms such as thirst, frequent urination, and fatigue. These effects are more pronounced in patients with diabetes or impaired glucose regulation.
4. Liver and Kidney Function Damage
During metabolism in the body, levofloxacin may affect liver and kidney functions. Regarding liver function, it may lead to elevated transaminase levels, causing symptoms such as dull pain in the liver area and loss of appetite. Concerning kidney function, it may impair glomerular filtration and tubular reabsorption, resulting in conditions such as proteinuria and elevated serum creatinine levels.
5. Psychiatric Abnormalities
This drug may affect the balance of neurotransmitters and the normal functioning of nerve cells in the central nervous system, leading to abnormal mental status and cognitive function. Some patients may experience psychiatric symptoms such as hallucinations, depression, insomnia, or confusion after taking the medication.
During treatment with levofloxacin, excessive exposure to sunlight should be avoided. When going outdoors, appropriate sun protection measures should be taken, such as wearing sun-protective clothing, hats, and applying sunscreen, to prevent photosensitivity reactions.
