Can a routine blood test detect norovirus?

Generally, a routine blood test cannot directly detect norovirus. The specific analysis is as follows:

A routine blood test primarily examines the cellular components in the blood, such as the quantity, morphology, and proportions of red blood cells, white blood cells, and platelets, to assess for conditions such as anemia, infection, or hematologic diseases. It can only reflect general conditions such as whether there is an inflammatory response in the body. For example, after a norovirus infection, a routine blood test might show a normal or slightly elevated total white blood cell count, and the lymphocyte percentage may show some changes, but these changes are not specific and cannot be used to diagnose a norovirus infection.

To confirm a norovirus infection, stool testing is usually required, such as detecting norovirus nucleic acid in the stool via real-time fluorescent quantitative PCR, or detecting norovirus antigens in the stool using methods like immune electron microscopy or enzyme-linked immunosorbent assay (ELISA). These methods can directly detect norovirus or its related components, thereby making a definitive diagnosis.

It is also important to maintain good hygiene practices, such as avoiding drinking untreated water, minimizing the consumption of raw and cold foods, and thoroughly washing fruits and vegetables before consumption. Additionally, develop the habit of washing hands frequently, especially before meals and after using the toilet or touching public items.