How many milliliters are donated in one blood donation?

Jun 24, 2025 Source: Cainiu Health
Dr. Liu Feng
Introduction
Under normal circumstances, a single blood donation usually ranges from 200 to 400 milliliters. Blood donation should be conducted at a正规 hospital. Please note that regardless of the chosen donation volume, donors must ensure they are in good health before donating blood, such as being free from colds, fever, or medication use, and must pass basic tests including blood pressure and routine blood analysis. After donating blood, pressure should be applied to the puncture site for 10–15 minutes to stop bleeding, and contact with water should be avoided on the same day to prevent infection.

Generally, a single blood donation typically ranges from 200 to 400 milliliters. Blood donation should be conducted at a formal medical institution. Detailed explanation is as follows:

Generally speaking, first-time donors, individuals with lower body weight, or those who feel anxious about donating blood are more suitable for a 200-milliliter donation. This helps reduce physical discomfort and allows gradual adaptation to the donation process. Conversely, donors who meet weight requirements, have good physical health, have no history of adverse reactions to previous donations, and are willing to donate may choose a 400-milliliter donation, which can more effectively assist in clinical treatment of patients.

It should be noted that regardless of the chosen donation volume, donors must ensure their own health status before donating—for example, no colds, fever, or medication use—and must pass basic tests such as blood pressure and routine blood tests. After donation, pressure should be applied to the puncture site for 10–15 minutes to stop bleeding. Contact with water should be avoided on the same day to prevent infection. If persistent discomfort occurs, medical attention should be sought promptly.

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