How to treat anemia in patients with rheumatoid arthritis
Nov 15, 2025
Source: Cainiu Health
Dr. Liu Feng
Introduction
Treatment options for anemia in patients with rheumatoid arthritis include controlling the underlying disease, iron supplementation, vitamin B12 and folic acid supplementation, use of erythropoietin, and dietary adjustments. Therapy should be standardized according to the type of anemia and severity of the condition. If anemia symptoms are significant or accompanied by dizziness and palpitations, prompt medical evaluation is recommended to determine the underlying cause.
Anemia in patients with rheumatoid arthritis can be managed through controlling the underlying disease, iron supplementation, vitamin B12 and folic acid supplementation, use of erythropoiesis-stimulating agents, dietary adjustments, and other approaches. Treatment should be standardized based on the type of anemia and severity of the condition. If anemia symptoms are significant or accompanied by dizziness and palpitations, prompt medical evaluation is recommended to determine the cause.
1. Control the primary disease: Anemia associated with rheumatoid arthritis is often linked to chronic inflammation. Proper use of anti-rheumatic medications to control joint inflammation helps reduce the inhibitory effects of inflammatory cytokines on hematopoiesis, thereby improving anemia at its root.
2. Iron supplementation: For iron-deficiency anemia, oral or injectable iron supplements should be taken under medical guidance to provide essential materials for blood cell production. Avoid concomitant use with medications that impair iron absorption to enhance iron utilization.
3. Vitamin B12 and folic acid supplementation: In cases of megaloblastic anemia,补充 vitamin B12 and folic acid helps correct deficiencies in hematopoietic nutrients, supports normal red blood cell production, and alleviates symptoms related to anemia.
4. Use of erythropoiesis-stimulating agents: For anemia of chronic disease or renal anemia, erythropoiesis-stimulating agents may be used after physician evaluation to stimulate bone marrow function, increase red blood cell counts, and improve anemic status.
5. Dietary adjustment: Increase daily intake of foods rich in iron, vitamin B12, and folic acid—such as red meat, animal liver, and fresh fruits and vegetables—to ensure balanced nutrition and support hematopoiesis, complementing pharmacological treatments.
During treatment, regular blood tests should be performed to monitor changes in anemia indicators; avoid excessive fatigue and ensure adequate sleep; engage in moderate, gentle exercise to promote circulation; and strictly follow medical instructions regarding medication without self-adjusting doses or discontinuing treatment.
