Is hepatic ascites liver cancer?

May 31, 2022 Source: Cainiu Health
Dr. Jin Zhongkui
Introduction
Hepatic ascites and hepatocellular carcinoma are two distinct diseases, yet they may co-occur. During the decompensated stage of liver cirrhosis, patients may develop splenomegaly, hypersplenism, and gastroesophageal varices. Hepatic ascites results from elevated portal pressure in cirrhotic patients, which increases resistance to blood flow returning from the gastrointestinal tract to the liver, leading to substantial fluid leakage into the peritoneal cavity.

Hepatic ascites is a chronic liver disease. When liver disease progresses to a certain stage, excessive fluid accumulates in the patient’s peritoneal cavity—this condition is termed “hepatic ascites,” as it results directly from underlying liver disease.

Is hepatic ascites the same as liver cancer?

Hepatic ascites and liver cancer are two distinct diseases, although they may co-occur. During the decompensated phase of cirrhosis, patients may develop splenomegaly, hypersplenism, and gastroesophageal varices. Hepatic ascites arises primarily from increased portal venous pressure in cirrhotic patients, which impedes blood flow returning from the gastrointestinal tract to the liver, leading to transudation of large volumes of fluid into the peritoneal cavity.

Treatment options for hepatic ascites include intravenous albumin infusion, diuretics, antibiotics, improvement of renal circulation, and autologous ascites reinfusion. Ascites formation is largely attributable to diminished hepatic synthesis of albumin, resulting in reduced plasma colloid osmotic pressure—thus promoting ascites accumulation. Diuretics enhance water excretion and facilitate ascites resolution. Large-volume ascites may compress the afferent arterioles of the glomeruli, thereby adversely affecting renal microcirculation. If conventional therapies prove ineffective, autologous ascites reinfusion may be considered.

Patients with hepatic ascites should adopt a regimen of small, frequent meals to reduce gastrointestinal burden. We hope this information proves helpful to you.


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