How to determine whether it's "big three positive" or "small three positive"

Nov 13, 2022 Source: Cainiu Health
Disease description:

My neighbor's uncle has hepatitis B, which I heard is contagious. I think he has the "minor three positives." I'd like to know how the "major three positives" and "minor three positives" are determined?

Doctor's answer (1)
Dr. Wang Dong
To determine whether it is "big three positive" or "small three positive," one can rely on the results of specific tests. In the hepatitis B two pairs and a half test, if both the hepatitis B core antibody and hepatitis B surface antigen are positive, along with a positive hepatitis B e-antigen, this typically indicates "big three positive." However, if the hepatitis B core antibody and hepatitis B surface antigen are positive but the e-antibody is negative, this usually refers to "small three positive."