How should membranous nephropathy syndrome be treated?

The treatment of membranous nephropathy in nephrotic syndrome should consider the severity of the condition and individual differences: 1. General treatment: Patients should ensure adequate rest, avoid excessive fatigue and infections, and follow a diet low in protein to reduce the burden on the kidneys. Additionally, blood pressure control, anticoagulant therapy, and lipid-lowering measures should be implemented. 2. Pharmacological therapy: Corticosteroids such as prednisone and methylprednisolone are foundational in suppressing immune and inflammatory responses. Immunosuppressants like cyclophosphamide and tacrolimus are often used in combination with corticosteroids to enhance therapeutic efficacy. Antihypertensive agents such as benazepril and valsartan help control blood pressure and reduce urinary protein excretion. Diuretics are used to alleviate edema, atorvastatin calcium improves lipid metabolism abnormalities, and warfarin sodium prevents thrombosis. 3. Symptomatic treatment: Tailored interventions should be provided according to specific symptoms such as edema and hyperlipidemia. 4. Hemodialysis: For patients with severe disease and poor response to medication, hemodialysis may be considered to maintain internal homeostasis.