What is the impact of gestational diabetes on the fetus?

Jul 16, 2024 Source: Cainiu Health
Disease description:

After my wife became pregnant, she developed gestational diabetes. What effects does diabetes during pregnancy have on the fetus?

Doctor's answer (1)
Dr. Zhao Xiaodong
The impacts of gestational diabetes on the fetus mainly include the following aspects: 1. Increased risk of fetal malformations: The incidence of fetal malformations in pregnant women with diabetes is higher than in those without diabetes, which may be related to abnormal embryonic development caused by hyperglycemia. Common malformations include defects in the cardiovascular system, nervous system, and digestive system. 2. Promotion of fetal macrosomia: Maternal hyperglycemia stimulates excessive synthesis of fetal proteins and fats, leading to overdevelopment of the fetal body and an increased incidence of macrosomia. 3. Increased risk of miscarriage and preterm birth: Hyperglycemia may cause abnormal embryonic development, ultimately leading to miscarriage. Additionally, complications such as polyhydramnios and gestational hypertension often necessitate early termination of pregnancy, increasing the risk of preterm birth. 4. Fetal growth restriction and distress: Hyperglycemia in early pregnancy may inhibit embryonic development, causing developmental delays. During mid to late pregnancy, diabetic ketoacidosis may occur, leading to fetal distress or even intrauterine fetal death. 5. Neonatal complications: These include neonatal hypoglycemia, hyperbilirubinemia, and respiratory distress syndrome, which may be associated with metabolic disturbances in the fetus caused by maternal hyperglycemia. Therefore, pregnant women should strictly control their blood glucose levels, undergo regular prenatal examinations, and receive necessary treatment under medical guidance to reduce the adverse effects of diabetes on the fetus.