How is vitiligo formed?
Disease description:
My father has developed white patches on his neck. After a hospital examination, he was diagnosed with vitiligo. I would like to understand how vitiligo develops.
Doctor's answer (1)
Dr. Wang Xiaoyan
Vitiligo, also known as leukoderma, has complex and not yet fully understood causes. The main possible factors include:
1. Genetic factors: Genetic factors are considered an important cause of vitiligo. If there is a family history of vitiligo, the risk of developing the condition in offspring increases.
2. Autoimmune factors: The patient's immune system may attack and destroy melanocytes, leading to pigment loss and the formation of white patches.
3. Neurological and psychological factors: Psychological factors are closely related to the onset of vitiligo. Psychological trauma or excessive stress may affect the function of melanocytes.
4. Physical injury: Chronic friction, severe burns, or significant trauma to the skin may result in damage or destruction of melanocytes.
5. Vitamin deficiency: Deficiencies, especially in vitamin B12 and folic acid, may be associated with the development of vitiligo.
