Can taking antihypertensive medications cause elevated uric acid levels?

Taking antihypertensive medications may potentially cause elevated uric acid levels, but not all antihypertensive drugs lead to this side effect. Specifically, some antihypertensive medications with diuretic effects, such as hydrochlorothiazide and indapamide, may reduce the excretion of uric acid, thereby increasing uric acid levels. However, the primary cause of elevated uric acid is usually an imbalance in purine metabolism within the body, leading to increased uric acid production or decreased excretion. Therefore, when using antihypertensive drugs, selection should be based on the patient's specific condition and the characteristics of the medication, and用药 should follow medical advice. At the same time, regular monitoring of uric acid levels is also necessary to promptly detect and manage any potential increase in uric acid. If elevated uric acid levels occur, timely medical consultation and treatment according to medical advice are required.