How is acute sepsis treated?

Acute sepsis is a severe systemic infection that occurs when pathogens such as bacteria, viruses, or fungi invade the bloodstream and trigger a systemic inflammatory response. The treatment of acute sepsis mainly includes the following aspects:

1. Etiological treatment: Based on the results of antimicrobial susceptibility testing, the most sensitive antimicrobial agents should be selected. Before the susceptibility results are available, empirical antimicrobial therapy may be initiated according to the patient's age, underlying disease type, immune status, and possible routes of pathogen invasion.

2. Removal of the infection source: Patients with localized infections, such as abscesses, biliary or urinary tract obstruction, should promptly undergo incision and drainage, needle aspiration, or surgical treatment to eliminate the source of infection.

3. Supportive therapy: This includes fluid resuscitation to maintain circulatory stability and internal environmental balance, immunological support such as intravenous immunoglobulin to enhance the body's defense mechanisms, as well as nutritional support, maintenance of water and electrolyte balance, and correction of acid-base disturbances.

4. Symptomatic treatment: For symptoms associated with acute sepsis, such as fever and pain, measures such as physical cooling and administration of nonsteroidal anti-inflammatory drugs may be used to alleviate symptoms.