Causes of Long-Term Amenorrhea
Jul 14, 2022
Source: Cainiu Health
Dr. Chen Zhe
Introduction
Prolonged absence of menstruation (amenorrhea) may be associated with endocrine imbalance and declining ovarian function. In women of childbearing age who are sexually active, pregnancy must be ruled out as a cause of missed periods. Additionally, organic lesions affecting the gynecological endocrine or reproductive systems should also be considered. Amenorrhea is primarily classified into two types: primary and secondary. Secondary amenorrhea—defined as the absence of menstruation for several consecutive months—is more common.
When women experience prolonged absence of menstruation (amenorrhea), they commonly develop symptoms such as anxiety, insomnia with frequent dreams, and decreased immunity. So, what are the causes of long-term amenorrhea?
Causes of Long-Term Amenorrhea
Prolonged amenorrhea may be associated with endocrine disorders or diminished ovarian function. In women of childbearing age who are sexually active, pregnancy must first be ruled out. Additionally, organic lesions affecting the gynecological endocrine or reproductive systems should also be considered. Amenorrhea is classified into two main types: primary and secondary. Secondary amenorrhea—defined as the absence of menstruation for several consecutive months—is far more common than primary amenorrhea.
The most common cause is hormonal imbalance—particularly luteal phase dysfunction—leading to persistent endometrial hyperplasia without subsequent withdrawal bleeding. If endometrial pathology is suspected, prompt medical evaluation is recommended, including relevant diagnostic tests to determine the underlying cause. Key investigations include pelvic ultrasound and serum hormone level assessments; endometrial biopsy may also be necessary in certain cases. Treatment varies depending on the specific diagnosis and may involve combined estrogen-progestin therapy—commonly referred to as “induced menstruation.”
Emotional distress or excessive stress can also disrupt menstrual regularity. To prevent abnormally heavy menstrual flow, it is advisable to undergo a comprehensive sex hormone panel (six key hormones) at a hospital to assess whether each hormone level falls within the normal range; traditional Chinese medicine (TCM) may then be used adjunctively for regulation. During menstruation, avoid consuming cold foods to reduce the risk of catching a cold or exacerbating fatigue. Medical treatment is essential. We hope this information proves helpful!
