How many doses of inactivated polio vaccine (IPV) are required?
Feb 18, 2022
Source: Cainiu Health
Dr. Li Yi
Introduction
Inactivated poliovirus vaccine (IPV) typically refers to the vaccine used to prevent poliomyelitis. A complete IPV immunization series usually consists of four doses. IPV is primarily administered to infants aged 2 months and older, with the optimal injection site being the anterolateral mid-thigh.
“IPV” stands for inactivated poliovirus vaccine, which is prepared by inactivating the poliovirus responsible for causing poliomyelitis. After inactivation, the virus loses its ability to infect. Below, we address the question: How many doses of IPV are required?
How many doses of IPV are required?
The inactivated poliovirus vaccine (IPV) typically requires a total of four doses.
IPV is manufactured by separately culturing types I, II, and III of the poliovirus in VERO cells, harvesting the viruses, concentrating and purifying them, and then inactivating them with formaldehyde. The three inactivated viral strains are subsequently mixed in defined proportions to produce a trivalent liquid vaccine. The final product appears as a clear, colorless liquid. Following administration, IPV induces active immunity in the recipient, thereby preventing poliomyelitis caused by poliovirus types 1, 2, and 3.
IPV is primarily indicated for infants aged two months and older. The optimal injection site is the anterolateral mid-thigh. A complete vaccination course consists of four doses: the first dose is administered at two months of age, followed by subsequent doses at three and four months of age, with a final booster dose given at 18 months of age.
Adverse reactions following IPV administration may include fever, headache, diarrhea, and occasionally rash; these symptoms generally resolve spontaneously within two to three days.
The above provides an overview of the recommended number of IPV doses. We hope this information is helpful to you.
