What medications can be used to induce menstruation when it is delayed?

Aug 24, 2022 Source: Cainiu Health
Dr. Lv Aiming
Introduction
For amenorrhea (absence of menstruation), sex hormone medications and ovulation-inducing drugs may be used to induce menstruation; however, such medications should only be administered after a definitive diagnosis has been established. Sex hormone medications—primarily estrogen and progesterone—are used to promote and maintain the patient’s secondary sexual characteristics and menstrual function, thereby supporting overall health and reproductive health. Progesterone is commonly administered as micronized progesterone or medroxyprogesterone acetate.

Under normal circumstances, the menstrual cycle lasts approximately 28 to 30 days, with variations of up to seven days earlier or later still considered within the normal range. However, if menstruation is significantly delayed or absent altogether, this may signal an underlying health issue, and prompt medical evaluation is recommended to identify the cause. So, what medications can be used to induce menstruation when it is absent?

Medications Used to Induce Menstruation When Periods Are Absent

Sex hormone medications (e.g., estrogen and progesterone) and ovulation-inducing agents may be prescribed to trigger menstruation—but only after a definitive diagnosis has been established. Sex hormone therapy primarily involves estrogen and progestin (e.g., progesterone or medroxyprogesterone acetate) to promote and maintain secondary sexual characteristics, regulate menstrual cycles, and support overall and reproductive health. Ovulation induction is mainly indicated for patients desiring fertility; commonly used agents include clomiphene citrate, bromocriptine, and gonadotropin-releasing hormone (GnRH) analogs. Clomiphene citrate is the most frequently prescribed ovulation-inducing drug. However, all such medications must be administered strictly under physician supervision—self-medication is strongly discouraged.

Glucocorticoids (e.g., prednisone or dexamethasone) are indicated for amenorrhea caused by congenital adrenal hyperplasia, typically administered in combination with these agents. Thyroid hormone replacement (e.g., levothyroxine or desiccated thyroid tablets) is appropriate for amenorrhea secondary to hypothyroidism. While these medications may help restore menstruation, their use must always be guided by a qualified healthcare professional.

In daily life, maintaining regular, balanced nutrition is essential. Avoid spicy, irritating foods and binge eating, and ensure adequate sleep by avoiding late-night activities. We hope this information proves helpful to you.

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