A 40-year-old female who has missed her period for three months.
A 40-year-old woman who has missed her period for three months may experience this due to non-disease factors, but it could also be related to medical conditions such as ovarian dysfunction or cervical adhesion. It is recommended to identify the underlying cause and receive treatment under a doctor's guidance. The specific analysis is as follows:
1. Non-disease factors
If a woman usually has regular menstrual cycles and engages in normal sexual activity without contraception, missing periods for three months warrants evaluation for possible pregnancy. If she has experienced a period of menstrual irregularity, this could be related to perimenopause, during which menstruation may stop for two to three months—or even up to six months—before suddenly resuming.
2. Disease-related factors
1) Ovarian dysfunction
The ovaries secrete estrogen, progesterone, and small amounts of androgens. When ovarian function is abnormal and androgen levels are elevated, conditions such as polycystic ovary syndrome (PCOS) or hyperprolactinemia may develop, potentially causing prolonged absence of menstruation. It is advisable to adjust diet and, under medical supervision, take oral progesterone capsules or receive intramuscular injections of progesterone solution. Note that these medications should not be used without medical advice to avoid potential medication risks.
2) Cervical adhesion
Damage and subsequent adhesion of the cervical canal mucosa can lead to cervical stenosis or closure, impairing the outflow of uterine secretions or menstrual blood. In severe cases, complete blockage may occur. If infection is confirmed as the cause, patients may follow a physician’s instructions to take antibiotics such as metronidazole tablets, amoxicillin capsules, or levofloxacin hydrochloride capsules. When necessary, cervical dilation using a dilator may be performed, and a urinary catheter may be placed postoperatively to prevent re-adhesion.
In addition, other conditions such as endocrine disorders or pelvic cancers may also cause the above symptoms. It is recommended to visit a gynecology department at a hospital and undergo relevant examinations—including complete blood count, sex hormone panel (six items), and pelvic ultrasound—to determine the cause and receive targeted treatment accordingly.