Which indicators should be checked for liver function and coagulation function?

Aug 01, 2023 Source: Cainiu Health

Dr. Yang Shuwen

Introduction

Liver function and coagulation status can be assessed by indicators such as thrombin time, fibrinogen, and prothrombin time. Liver function related to coagulation generally refers to the blood clotting ability of the liver. For instance, if the thrombin time is prolonged, it indicates stronger coagulation capacity in the patient, which may impair normal blood flow. In such cases, anticoagulant medications such as argatroban injection or bivalirudin for injection should be administered promptly as directed by a physician.

　　Liver function and coagulation status can be assessed by indicators such as thrombin time, fibrinogen, and prothrombin time. Specific analysis is as follows:

　　1. Thrombin Time

　　Liver function-related coagulation capacity generally refers to the blood clotting ability in the liver region, which can be evaluated by measuring thrombin time. If thrombin time is prolonged, it indicates reduced clotting ability, potentially leading to impaired normal blood flow. In such cases, patients should promptly follow medical advice to use medications such as argatroban injection or bivalirudin for injection.

　　2. Fibrinogen

　　Fibrinogen is a protein molecule produced in the human liver and directly participates in liver-related coagulation functions. Its levels may be influenced by factors such as aging, environmental conditions, and underlying diseases. Therefore, patients usually require further diagnostic tests—such as complete blood count (CBC) and ultrasound imaging—to identify the exact cause and receive targeted treatment.

　　3. Prothrombin Time

　　Prothrombin time measures the speed of blood clotting after platelets are removed from plasma. This value can be affected by congenital genetic conditions, jaundice, thrombosis, and other factors. Results that are higher or lower than the normal range indicate abnormalities in these conditions.

　　In addition, other indicators such as transaminases, albumin, and globulin can also be used to evaluate liver function. It is recommended to seek timely medical attention if any of these indicators show abnormalities.

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