What causes liver function deterioration?

Under normal circumstances, liver function deterioration may be caused by factors such as aging, chronic sleep deprivation, non-alcoholic fatty liver disease, chronic hepatitis B, or autoimmune hepatitis. If discomfort symptoms occur, it is recommended to seek timely medical evaluation and treatment at a qualified hospital. Detailed analysis is as follows:

1. Aging

With increasing age, the liver cells' regenerative capacity weakens and metabolic efficiency declines, gradually leading to functional deterioration. Maintain a balanced diet rich in vitamin-containing fruits and vegetables, follow regular作息 (daily routines), avoid excessive fatigue, and undergo a liver function test annually.

2. Chronic Sleep Deprivation

The nighttime hours are critical for liver cell repair. Staying up late disrupts metabolic rhythms, causing liver cell damage and resulting in functional decline. Establish a fixed daily sleep schedule, ensure 7–8 hours of sleep, avoid coffee or strong tea before bedtime, and consider foot soaking to promote sleep.

3. Non-Alcoholic Fatty Liver Disease

Accumulation of fat within liver cells compresses normal cellular space, impairing metabolic function and leading to deterioration. Control intake of high-fat and high-sugar foods, increase aerobic exercises such as jogging or swimming, and take medications such as silibinin capsules, polyene phosphatidylcholine capsules, or enteric-coated diammonium glycyrrhizinate capsules as directed by a physician.

4. Chronic Hepatitis B

Persistent replication of the hepatitis B virus damages liver cell structures, leading to hepatocyte necrosis and gradual deterioration of liver function. Long-term standardized treatment is required. Medications such as entecavir tablets, tenofovir alafenamide fumarate tablets, or lamivudine tablets may be taken under medical guidance. Alcohol consumption should be avoided.

5. Autoimmune Hepatitis

Abnormal immune system activity attacks liver cells, triggering chronic inflammation that leads to long-term damage and functional deterioration. Treatment may include prednisone tablets, azathioprine tablets, or mycophenolate mofetil dispersible tablets as prescribed. Regular monitoring of liver function and immune markers is essential, and in severe cases, liver transplantation may be necessary.

Adopt healthy lifestyle habits in daily life to reduce the burden on the liver. Avoid indiscriminate use of medications; always consult healthcare professionals before taking any drugs. Maintain emotional well-being and avoid prolonged anxiety. Schedule regular health check-ups to detect problems early and intervene promptly, thereby protecting liver health.