How to interpret a five-item liver function test report
Oct 25, 2023
Source: Cainiu Health
Dr. Wang Xuemei
Introduction
Normally, a liver function panel (five-item test) primarily evaluates the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin, direct bilirubin, and indirect bilirubin. Note that after receiving your liver function test results, you should promptly consult a qualified physician to determine whether any abnormalities indicate underlying health issues. Additionally, it is recommended to fast before undergoing liver function tests to avoid affecting the accuracy of the results.
Liver function tests typically evaluate the levels of five key indicators: alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin, direct bilirubin, and indirect bilirubin. The specific details are as follows:
1. Alanine Aminotransferase (ALT)
The normal range for ALT is generally 0–40 U/L. Elevated ALT levels may indicate liver damage, which can be caused by factors such as chronic sleep deprivation, excessive fatigue, or viral hepatitis.
2. Aspartate Aminotransferase (AST)
The normal AST level for adult males is 0–40 U/L, and for females, it is 0–35 U/L. Elevated AST levels may suggest liver disease, such as viral hepatitis or alcoholic liver disease, and patients may experience symptoms including loss of appetite, abdominal bloating, and vomiting.
3. Total Bilirubin
The normal range for total bilirubin in healthy adults is 3.4–17.1 μmol/L. Elevated total bilirubin levels may result from conditions such as bile duct obstruction or cholestasis.
4. Direct Bilirubin
The normal range for direct bilirubin is 0–6.8 μmol/L. Levels exceeding 6.8 μmol/L may be due to bile duct obstruction or cholestasis.
5. Indirect Bilirubin
The normal range for indirect bilirubin is 0–12 μmol/L. Elevated indirect bilirubin levels indicate abnormal liver function and may be caused by hemolytic jaundice or hepatocellular jaundice.
Note: After receiving your liver function test results, consult a qualified physician promptly to determine whether any abnormalities require treatment. Additionally, it is recommended to undergo liver function testing on an empty stomach to ensure accurate results.
