What are bisphosphonate drugs?

Feb 03, 2024 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Under normal circumstances, bisphosphonate medications include clodronate disodium tablets, alendronate sodium tablets, risedronate sodium tablets, zoledronic acid injection, and teriparatide injection. These medications should be used only as directed by a physician. If any adverse reactions occur after taking the medication, prompt medical attention is recommended. Regardless of which medication is used, patients should always use them under a doctor's guidance or supervision.

Generally, bisphosphonate medications include clodronate disodium tablets, alendronate sodium tablets, risedronate sodium tablets, zoledronic acid injection, and teriparatide injection. These medications should be used only as directed by a physician. If any adverse reactions occur after taking the medication, prompt medical attention is recommended. The details are as follows:

1. Clodronate Disodium Tablets

Clodronate disodium tablets are a type of bisphosphonate drug that primarily works by inhibiting the activity of bone-resorbing cells, thereby reducing bone resorption and increasing bone density. They can be used to treat various types of osteoporosis.

2. Alendronate Sodium Tablets

Alendronate sodium tablets are also a bisphosphonate medication. By inhibiting bone-resorbing cells, they slow the progression of osteoporosis, helping to preserve bone tissue and improve bone quality. They are used to treat postmenopausal osteoporosis in women and can also prevent osteoporosis in men. Additionally, they are effective in treating glucocorticoid-induced osteoporosis.

3. Risedronate Sodium Tablets

Risedronate sodium tablets belong to the third generation of bisphosphonates. They improve bone metabolism by inhibiting bone-resorbing cells and regulating bone formation. They are indicated for the treatment of osteoporosis, including postmenopausal osteoporosis and osteoporosis in male patients.

4. Zoledronic Acid Injection

Zoledronic acid injection is a newer-generation bisphosphonate that slows bone loss by inhibiting bone-resorbing cells. It is primarily used to treat multiple myeloma and bone metastatic diseases, such as those associated with breast cancer and prostate cancer.

5. Teriparatide Injection

Teriparatide is a bone resorption inhibitor that regulates bone metabolism and suppresses bone resorption. It can be used to treat multiple myeloma, particularly in patients who have not responded to or cannot tolerate other treatments.

Regardless of which medication is used, patients must follow medical guidance or have procedures performed under a doctor's supervision. Self-medication should be avoided to prevent potential harm caused by inappropriate drug use.