What does an elevated erythrocyte sedimentation rate (ESR) mean?

In general, an elevated erythrocyte sedimentation rate (ESR) may be associated with factors such as aging, pregnancy, anemia, systemic lupus erythematosus, and coronary atherosclerotic heart disease. It is recommended to seek medical attention promptly and receive appropriate treatments—such as general management and medication—under the guidance of a physician. Specific analyses are as follows:

1. Aging

With advancing age, changes in hormone levels within the body can affect blood composition. For example, increased fibrinogen concentration may enhance red blood cell aggregation, thereby increasing the ESR. Special treatment is usually not required; however, regular monitoring of ESR and other related health indicators is advised.

2. Pregnancy

During pregnancy, hormonal changes and increased blood volume may lead to hemodilution and decreased hematocrit, which can accelerate ESR, commonly resulting in elevated levels. Proper prenatal care should be maintained, along with regular check-ups to monitor ESR and other health parameters.

3. Anemia

Anemia may result from deficiencies in folic acid or vitamin B12, excessive red blood cell destruction, or other causes. A reduced number of red blood cells decreases the blood's oxygen-carrying capacity, while levels of acute-phase reactants in plasma rise, contributing to faster ESR. Symptoms may include pallor, fatigue, palpitations, and others. Patients may take medications such as ferrous sulfate tablets, compound ferrous sulfate granules, or ferrous fumarate tablets as directed by a physician.

4. Systemic Lupus Erythematosus (SLE)

Factors such as weakened immunity, excessive sun exposure, and infections may trigger SLE. Autoimmune reactions activate the release of inflammatory mediators, increasing acute-phase reactants in plasma and affecting red blood cell aggregation, thus elevating ESR. This condition is often accompanied by symptoms like joint pain, swelling, and photosensitivity. Under medical supervision, patients may use medications such as ibuprofen sustained-release capsules, aspirin tablets, or indomethacin tablets for treatment.

5. Coronary Atherosclerotic Heart Disease

Excessive physical exertion, overeating, cold exposure, smoking, and other factors may contribute to coronary atherosclerotic heart disease, potentially causing narrowing or blockage of blood vessels and high cholesterol levels. These changes may lead to symptoms including angina pectoris. Under a doctor’s advice, patients may use medications such as nitroglycerin tablets, isosorbide mononitrate sustained-release tablets, or enteric-coated aspirin tablets.

In daily life, it is important to maintain healthy作息 habits, appropriately relax the mind, stay positive when facing challenges, and engage in regular physical activity to help manage emotional well-being.