What medications are used for IgA nephropathy?
Mar 19, 2025
Source: Cainiu Health
Dr. Yang Guang
Introduction
IgA nephropathy can be managed with antihypertensive therapy using Captopril tablets, anti-infective treatment with Amoxicillin and Clavulanate Potassium tablets, anti-inflammatory therapy with Prednisone acetate tablets, and immunosuppressive therapy with Azathioprine tablets. Additionally, Aspirin enteric-coated tablets may be used to inhibit platelet aggregation, helping to alleviate symptoms, control disease progression, and further reduce kidney damage.
Generally, IgA nephropathy is a primary glomerular disease with an unclear cause, possibly related to infections. When treating this condition, medications such as captopril tablets, amoxicillin-clavulanate potassium tablets, prednisone acetate tablets, azathioprine tablets, and aspirin enteric-coated tablets may be used under a doctor's guidance. If any discomfort occurs, timely medical consultation and relevant examinations are recommended. Detailed analysis is as follows:
1. Captopril Tablets
Captopril tablets are antihypertensive medications primarily used to control blood pressure, helping to reduce the damage caused by elevated blood pressure in patients with IgA nephropathy. This is achieved by reducing the production of angiotensin II. However, long-term use may cause side effects such as coughing and dizziness.
2. Amoxicillin-Clavulanate Potassium Tablets
Amoxicillin-clavulanate potassium tablets are antibiotics. When patients with IgA nephropathy have concurrent infections, antibiotics are needed to control the infection and prevent further worsening of the condition. This works by inhibiting bacterial cell wall synthesis. However, occasional adverse effects after administration include gastrointestinal discomfort, allergic reactions, and even damage to liver and kidney function.
3. Prednisone Acetate Tablets
Prednisone acetate tablets belong to the glucocorticoid class of medications. They can inhibit the proliferation of T and B lymphocytes and have anti-inflammatory effects, helping patients with IgA nephropathy control inflammatory responses and reduce kidney damage. However, long-term use can easily lead to immunosuppression and induce osteoporosis.
4. Azathioprine Tablets
Azathioprine tablets are immunosuppressive agents that can reduce kidney damage by inhibiting the proliferation and activation of immune cells, thereby assisting in alleviating symptoms related to IgA nephropathy. However, some patients may experience impaired liver function after taking this medication, causing symptoms such as jaundice and fatigue.
5. Aspirin Enteric-Coated Tablets
Aspirin enteric-coated tablets belong to antiplatelet agents. When IgA nephropathy patients exhibit mild proteinuria or hematuria, this medication is used to prevent platelet aggregation and inhibit thrombus formation, thus protecting kidney function. However, long-term use may easily cause gastrointestinal bleeding and coagulation disorders.
With timely treatment, the prognosis of IgA nephropathy is generally good. Therefore, maintaining an optimistic mindset during treatment is important. Additionally, regular monitoring is necessary when using the above medications, and any medication causing discomfort should be discontinued promptly.
