Are there any side effects of glutamine?

Under normal circumstances, glutamine may have certain side effects. The specific analysis is as follows:

As an amino acid, glutamine participates in various metabolic processes in the human body; however, excessive or improper intake may easily cause discomfort. When intestinal absorption capacity is limited, excess glutamine can irritate the mucosa, leading to gastrointestinal reactions such as bloating and diarrhea. Individuals with unique metabolic pathways may experience increased metabolic burden on the liver and kidneys with long-term supplementation, potentially resulting in abnormal laboratory indicators. In people with immune system disorders, glutamine intake might disrupt immune balance and trigger mild inflammatory responses, such as rashes or low-grade fever. These reactions are closely related to individual tolerance levels and dosage control.

During use, single doses should be carefully controlled within the recommended range to avoid overdose. Taking glutamine after meals can reduce gastrointestinal irritation. It is also advisable to maintain a light and easily digestible diet while avoiding spicy and greasy foods. Regular monitoring of physical condition is important; if persistent discomfort occurs, discontinue use immediately and consult a healthcare professional. Maintaining adequate hydration supports the elimination of metabolic byproducts, while regular sleep patterns and moderate exercise can enhance the body's tolerance and reduce the risk of adverse effects.