Is an ALT level of 72 U/L severe?

Generally speaking, whether an ALT level of 72 U/L is serious depends on the specific cause and accompanying symptoms. The detailed analysis is as follows:

If the ALT level of 72 U/L results from recent factors such as staying up late, alcohol consumption, intense exercise, or taking medications that may harm the liver, and there are no obvious discomforts, it is usually not considered serious. These cases are mostly due to physiological or transient damage, without ongoing destruction of liver cells. After eliminating the triggering factors, the ALT levels typically return to normal gradually with short-term lifestyle adjustments, so there's no need for excessive concern.

However, if symptoms such as fatigue, jaundice, or abdominal pain are present, or if there is an underlying liver condition like hepatitis B or fatty liver disease, an ALT level of 72 U/L should be taken seriously. This may indicate active liver inflammation and ongoing hepatocellular injury. Without timely intervention, the condition could worsen. Further diagnostic tests are needed to identify the cause and initiate appropriate treatment.

For individuals without symptoms or pre-existing liver disease, it is recommended to repeat the test after 1–2 weeks while avoiding alcohol and late nights. Those with symptoms or high-risk factors should undergo additional evaluations, including hepatitis markers and liver ultrasound, to determine the underlying cause and receive proper treatment.