Changes in the five items of hepatitis B testing after hepatitis B vaccination

Apr 12, 2023 Source: Cainiu Health
Dr. Jiang Weimin
Introduction
Hepatitis B vaccine is an effective method to prevent hepatitis B virus infection. After receiving the hepatitis B vaccine, the results typically show: hepatitis B surface antigen negative, hepatitis B surface antibody positive, hepatitis B e-antigen negative, hepatitis B e-antibody positive, and hepatitis B core antibody positive. Following vaccination, these five markers usually indicate the development of immunity against the hepatitis B virus.

Hepatitis B vaccine is an effective method to prevent hepatitis B virus infection. After receiving the hepatitis B vaccine, the test results typically show: hepatitis B surface antigen negative, hepatitis B surface antibody positive, hepatitis B e-antigen negative, hepatitis B e-antibody positive, and hepatitis B core antibody positive. Specifically:

1. Hepatitis B Surface Antigen (HBsAg)

After vaccination, the hepatitis B surface antigen test result is usually negative, indicating no hepatitis B virus infection.

2. Hepatitis B Surface Antibody (anti-HBs)

After vaccination, the hepatitis B surface antibody test result is usually positive, indicating the development of antibodies against the hepatitis B surface antigen and the presence of immunity.

3. Hepatitis B e-Antigen (HBeAg)

After vaccination, the hepatitis B e-antigen test result is usually negative, indicating no active hepatitis B virus infection.

4. Hepatitis B e-Antibody (anti-HBe)

After vaccination, the hepatitis B e-antibody test result is usually positive, indicating the development of antibodies against the hepatitis B e-antigen and the presence of immunity.

5. Hepatitis B Core Antibody (anti-HBc)

After vaccination, the hepatitis B core antibody test result is usually positive, indicating the development of antibodies against the hepatitis B core antigen and the presence of immunity.

Following hepatitis B vaccination, the typical changes in the five hepatitis B markers indicate the development of immunity against the hepatitis B virus, thereby reducing the risk of hepatitis B infection.


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