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Under what circumstances should a cone biopsy be performed for HPV infection?

May 04, 2023 Source: Cainiu Health
Dr. Lv Aiming
Introduction
Conization refers to cervical conization surgery, which is performed in cases of HPV infection with cervical intraepithelial neoplasia, precancerous cervical lesions, or vaginal intraepithelial neoplasia. When cervical intraepithelial neoplasia is severe, the cervical conization procedure removes the abnormal cervical tissue. For precancerous cervical lesions that may progress to cervical cancer, conization helps eliminate the lesion and reduce the risk of developing cervical cancer. Vaginal intraepithelial neoplasia can also be treated by excising the affected tissue via cervical conization.

Cervical conization generally refers to a surgical procedure known as cervical conization. This procedure is recommended in cases of HPV infection accompanied by cervical intraepithelial neoplasia, precancerous cervical lesions, vaginal intraepithelial neoplasia, and similar conditions. The specifics are analyzed as follows:

1. Cervical Intraepithelial Neoplasia (CIN)

Cervical intraepithelial neoplasia is a precancerous condition of the cervix. When the lesion is high-grade or severe, cervical conization can be performed to remove the abnormal cervical tissue. Additionally, the excised tissue can undergo pathological examination to determine the extent and nature of the lesion, thereby enabling early prevention and treatment of cervical cancer.

2. Precancerous Cervical Lesions

This refers to abnormal proliferation of cervical epithelial cells, which, if left untreated, may progress to cervical cancer. It is recommended that under the guidance of a qualified physician, cervical conization be performed to remove the abnormal cells in the affected area, reducing the risk of developing cervical cancer.

3. Vaginal Intraepithelial Neoplasia (VAIN)

If not actively treated, vaginal intraepithelial neoplasia may progress into more serious cancers. It is advised that, under the care of a specialist, cervical conization be used to remove the diseased tissue, followed by pathological examination to determine whether precancerous changes or early-stage cancer are present, thus helping guide subsequent treatment.

In addition, when diseases such as vulvar intraepithelial neoplasia, urethral orifice intraepithelial neoplasia, and perianal intraepithelial neoplasia have reached a high-grade or severe stage, cervical conization may also be required. Treatment should be performed by qualified medical professionals to promote symptom relief and recovery.

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