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Why emotions can cause various diseases

Nov 20, 2025 Source: Cainiu Health
Dr. Zhang Baohua
Introduction
Emotions can trigger various diseases, generally related to factors such as emotional impacts on neurotransmitter secretion, disruption of endocrine balance, and weakening of immune system function. Prolonged negative emotions can lead to imbalances in neurotransmitters such as serotonin and dopamine in the brain. These substances regulate mood and bodily functions; when imbalanced, they may cause sleep disorders, anxiety, depression, and other issues, and can also indirectly affect pain perception.

Emotions can trigger various diseases, generally related to factors such as emotional impact on neurotransmitter secretion, disruption of endocrine balance, weakening of immune system function, increased burden on the cardiovascular system, and interference with digestive system function. A detailed analysis is as follows:

1. Emotional impact on neurotransmitter secretion: Prolonged negative emotions can lead to imbalances in neurotransmitters such as serotonin and dopamine in the brain. These substances regulate mood and bodily functions; when disrupted, they may cause sleep disorders, anxiety, depression, and also indirectly affect pain perception, worsening physical discomfort.

2. Disruption of endocrine balance: Intense or persistent emotional fluctuations stimulate the adrenal glands to secrete hormones such as cortisol. Long-term hormonal imbalances can impair metabolic functions, potentially leading to elevated blood sugar, abnormal weight changes, and thyroid dysfunction, resulting in symptoms like fatigue and low mood.

3. Weakening of immune system function: Negative emotions suppress the activity of immune cells, reducing the body's ability to defend against pathogens. This increases susceptibility to infections and may disrupt regulation of inflammatory responses, leading to chronic inflammation and exacerbating symptoms of chronic conditions such as arthritis and asthma.

4. Increased burden on the cardiovascular system: During emotional arousal, heart rate increases and blood pressure rises. Over time, this can damage vascular endothelium, increase the risk of atherosclerosis, induce arrhythmias, and even trigger serious cardiovascular events such as angina pectoris and myocardial infarction.

5. Interference with digestive system function: Emotional stress or depression can disrupt gastrointestinal motility and secretion of digestive fluids, potentially causing indigestion, bloating, and stomach pain. Over the long term, it may also disturb the balance of gut microbiota, worsening digestive disorders such as irritable bowel syndrome.

It is important to pay attention to emotional changes in daily life and regulate emotions through physical activity, social interaction, hobbies, and other methods. If negative emotions persist and cause noticeable physical discomfort, it is advisable to seek psychological or medical support promptly to prevent further adverse effects on physical health.

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