Is it serious if uterine fibroids cause absence of menstruation?

Nov 14, 2025 Source: Cainiu Health

Dr. Zhang Lu

Introduction

If uterine fibroids are small in size and located subserosally (not invading the uterine cavity), and only slightly affect endometrial shedding leading to delayed or temporarily absent menstruation, menstrual cycles can usually gradually return to normal through medication regulation or regular monitoring—especially when the fibroids show no significant growth. In such cases, the impact on fertility and overall health is minimal, and the condition is not considered serious.

Generally, if uterine fibroids cause amenorrhea (absence of menstruation), the condition is usually not serious when the fibroids are small and do not significantly affect the uterine structure, especially if timely intervention is provided. However, if the fibroids are large or located in critical areas and are left untreated, the situation may become more severe. If there are concerns, it is recommended to seek medical consultation early. Detailed analysis is as follows:

If the uterine fibroid is small and grows subserosally (without invading the uterine cavity), and only slightly affects endometrial shedding leading to delayed or temporarily absent menstruation, the menstrual cycle can usually gradually return to normal through medication or regular monitoring—provided the fibroid does not significantly increase in size. In such cases, the impact on fertility and overall health is minimal, and the condition is generally not considered serious.

If the fibroid is large or located in the submucosal region (protruding into the uterine cavity) or within the myometrium (interfering with uterine contractions), it may distort the uterine cavity, alter the surface area of the endometrium, or compress the ovaries affecting hormone secretion. This can lead to prolonged absence of menstruation, possibly accompanied by complications such as anemia or infertility. Without timely treatment, there may also be an increased risk of malignant transformation of the fibroid. Such cases are considered more serious.

Once amenorrhea caused by uterine fibroids is detected, prompt ultrasound examination should be performed to determine the size and location of the fibroid. Treatment—whether pharmacological or surgical—should be decided according to medical advice.

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